Alkyl chlorides
Aobchem 2 2-Difluoro-1-(2 3 6-trifluorophenyl)ethanone | ≥97% | CAS 2229391-91-5 | C8H3F5O | 500mg
2 2-Difluoro-1-(2 3 6-trifluorophenyl)ethanone | ≥97% | CAS 2229391-91-5 | C8H3F5O | 500mg
Aobchem 2 5-Dichloro-N-(2 2 2-trifluoroethyl)benzamide | 95% | CAS 1625282-08-7 | C9H6Cl2F3NO | 250mg
2 5-Dichloro-N-(2 2 2-trifluoroethyl)benzamide | 95% | CAS 1625282-08-7 | C9H6Cl2F3NO | 250mg
Aobchem (3-Ethoxy-2-fluoro-6-(trifluoromethyl)phenyl)boronic acid | 97% | C9H9BF4O3 | 1g
(3-Ethoxy-2-fluoro-6-(trifluoromethyl)phenyl)boronic acid | 97% | C9H9BF4O3 | 1g
Aobchem 4-(1-Pyrrolidinyl)-3-(trifluoromethyl)benzaldehyde | ≥97% | CAS 886500-73-8 | C12H12F3NO | 5g
4-(1-Pyrrolidinyl)-3-(trifluoromethyl)benzaldehyde | ≥97% | CAS 886500-73-8 | C12H12F3NO | 5g
Aobchem 2 2 2-Trichloro-1-(4-fluorophenyl)ethanol | 95% | CAS 394-56-9 | C8H6Cl3FO | 250mg
2 2 2-Trichloro-1-(4-fluorophenyl)ethanol | 95% | CAS 394-56-9 | C8H6Cl3FO | 250mg
Aobchem 3 4 5-Trichloro-benzoicacid | ≥97% | CAS 51-39-8 | C7H3Cl3O2 | 25g
3 4 5-Trichloro-benzoicacid | ≥97% | CAS 51-39-8 | C7H3Cl3O2 | 25g
Aobchem N-(2-Methylpropyl)-4-(trifluoromethyl)benzenemethanamine | ≥95% | CAS 637359-15-0 | C12H16F3N | 250mg
N-(2-Methylpropyl)-4-(trifluoromethyl)benzenemethanamine | ≥95% | CAS 637359-15-0 | C12H16F3N | 250mg
Aobchem 1-(Methylsulfonyl)-4-(trifluoromethyl)benzene | ≥95% | CAS 145963-48-0 | C8H7F3O2S | 5g
1-(Methylsulfonyl)-4-(trifluoromethyl)benzene | ≥95% | CAS 145963-48-0 | C8H7F3O2S | 5g
Aobchem Methyl 2 4 6-trichloro- -oxobenzeneacetate | 95% | CAS 1599538-88-1 | C9H5Cl3O3 | 1g
Methyl 2 4 6-trichloro- -oxobenzeneacetate | 95% | CAS 1599538-88-1 | C9H5Cl3O3 | 1g
Aobchem (3-Ethoxy-2-fluoro-6-(trifluoromethyl)phenyl)(methyl)sulfane | 95% | CAS 2710879-38-0 | C10H10F4OS | 250mg
(3-Ethoxy-2-fluoro-6-(trifluoromethyl)phenyl)(methyl)sulfane | 95% | CAS 2710879-38-0 | C10H10F4OS | 250mg
Medchemexpress LLC Spi-112 | 1051387-90-6 | MFCD31620831 | 98.0% | 468.46 g/mol | C22H17FN4O5S | 1 ML
SPI-112 is a potent, selective, and competitive inhibitor of SHP2 (PTPN11) used for in vitro biochemical and biophysical studies. It inhibits SHP2 with an IC50 of approximately 1 μM, with weaker activity against related phosphatases. Kinetic and binding data indicate competitive inhibition (Ki ≈ 0.8 μM) and 1:1 binding by SPR (KD ≈ 1.3 μM). The compound is not cell permeable and is supplied for research applications.
- Inhibits SHP2 with IC50 ≈ 1 μM.
- Shows selectivity over related phosphatases (IC50s 18.3 μM for PTP, 14.5 μM for PTP1B).
- Exhibits competitive inhibition kinetics (Ki ≈ 0.8 μM).
- Binds 1:1 in SPR with KD ≈ 1.3 μM.
- Not cell permeable due to polar or charged functional groups.
- Supplied as a solid and as a 10 mM solution for in vitro assays.
- High purity suitable for biochemical assays (≈98%).
- Store solid at 4°C; in solvent store at -80°C (long term) or -20°C (short term).
Medchemexpress LLC hsa-miR-122-5p mimic 20nmol | 20nmol
hsa-miR-122-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
Aobchem 2 2 2-Trichloro-1-(3-chloro-5-methylphenyl)ethanol | 95% | CAS 116069-81-9 | C9H8Cl4O | 1g
2 2 2-Trichloro-1-(3-chloro-5-methylphenyl)ethanol | 95% | CAS 116069-81-9 | C9H8Cl4O | 1g
Aobchem Ethyl 2-oxo-2-(2 4 5-trichlorophenyl)acetate | 95% | CAS 887267-32-5 | C10H7Cl3O3 | 1g
Ethyl 2-oxo-2-(2 4 5-trichlorophenyl)acetate | 95% | CAS 887267-32-5 | C10H7Cl3O3 | 1g